Herbal Supplements and Sedatives: A Potentially Dangerous Combination

The use of herbal supplements has increased significantly, with almost 17.9% of US adults using them in 2012. Most people view supplements as harmless. Yet, research has shown that commonly-used supplements can lead to dangerous interactions with prescription and sedative medications. To tackle this unexcepted risk, drug interaction tools have incorporated details on natural products. Here are a few examples of supplements that can be life-threatening when used with sedatives.

St. John’s Wort

St. John’s Wort is often used as a therapy for depression, anxiety, and insomnia; however, it’s not safe for everyone. In a 2012 analysis of herb-drug interactions, it was discovered that St. John’s Wort had a considerable likelihood of unfavourable drug interactions. For example, it significantly lowers the serum concentration of up to 20 different types of drugs and decrease the efficacy of sedatives.

Feverfew

Feverfew is found in many herbal teas and is frequently used as a migraine remedy. However, it is essential to note that prolonged use may slow down blood clotting. Therefore, patients who regularly consume feverfew are advised to discontinue at least two weeks before any surgical procedures to avoid complications.

Valerian

Valerian is commonly used in calming or sedative supplements and can have negative effects when combined with benzodiazepines, CNS depressants, or medications that affect blood clotting. Some individuals take valerian before anxiety-provoking situations, such as dental appointments, which can lead to excessive sedation.

Kava

Kava is commonly used due to its anxiolytic and analgesic qualities. Despite its benefits, it is important to be aware of the risks. When taken with sedatives, kava may intensify its effects, and when taken alongside NSAIDs or statins can increase the risk of liver damage.

Patients may unknowingly consume herbal supplements that can alter their response to treatment. This emphasizes the importance of obtaining an accurate medical history by asking about their use. It’s crucial to provide patients with information about these products before treatment. Since not all interactions have been thoroughly studied, monitoring vital signs and blood clotting carefully during procedures is critical.